Antimicrobial resistance (AMR) is emerging as a global threat to public health.One of the strategies employed to combat AMR is the use of adjuvants which act to enhance or reinstate antimicrobial activity by inhibiting resistance mechanisms.However, these adjuvants are themselves not immune to selecting resistant phenotypes.Thus, there is a need to

Human cytomegalovirus (HCMV) is a high-risk pathogen in immunocompromised individuals, especially in transplant recipients.HCMV viremia must be monitored, and frequently, patients are treated with antiviral agents.HCMV has a variety of strategies to modulate host antiviral responses, and one important player is a viral homolog of the cellular inter

Introduction: Chronic kidney disease (CKD) is described by structural or functional defects staying for three months.End-stage kidney disease (ESKD) patients undergoing renal replacement therapy (RRT) face complications and increased susceptibility to infections due to their compromised immune system.In addition, malnutrition and chronic inflammato

Motility is finely regulated and is crucial to bacterial processes including colonization and biofilm formation.There is a trade-off between motility and growth in bacteria with molecular mechanisms not fully understood.Hypermotile Escherichia coli could be isolated by evolving non-motile cells on soft agar plates.Most of the isolates carried mutat